Patricia T. Arquette (born April 8, 1968) is an American actress currently starring in the supernatural drama Medium.
Arquette was born in Chicago, Illinois, and was raised in Virginia and California. She is the daughter of Brenda "Mardi" Olivia (née Nowak), an actress, poet, theater operator, activist, acting teacher and therapist; and actor Lewis Arquette. Arquette's paternal grandfather was comedian Cliff Arquette. Arquette's mother was Jewish, the daughter of a Holocaust refugee from Poland, and Arquette's father was a convert to Islam and a descendant of explorer Meriwether Lewis. Arquette's siblings are actors Rosanna, Alexis, Richmond and David Arquette. Arquette is also the sister-in-law of Courteney Cox, who is married to her brother David.
In April 1995, Arquette married Nicolas Cage (with whom she would later co-star in Bringing Out the Dead in 1999). They separated after nine months, but acted as a couple in public until Cage filed for divorce in February 2000. The divorce petition was withdrawn, but Arquette filed again in November 2000.
In 1997, after her mother died of breast cancer, Arquette worked to raise awareness about the disease. She has run in the annual Race for the Cure, and in 1999 was the spokesperson for Lee National Denim Day, which raises millions of dollars for breast cancer research and education.
Arquette has a son, Enzo (born January 3, 1989) with musician Paul Rossi.
While filming Holes she discovered she was pregnant. Daughter Harlow Olivia Calliope Jane was born on February 20, 2003. She and actor Thomas Jane became engaged in 2002 and married on June 25, 2006 at the Palazzo Contarini in Venice, Italy. Arquette filed for divorce from Jane on the grounds of irreconcilable differences in January 2009